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Although TR/GR-null livers generate some of their cysteine through the serine transsulfuration pathway, we here show that most cysteine in TR/GR-null livers comes from a pathway in which pyridoxal-phosphate-dependent cleavage of a carbonsulfur bond in cystine generates cysteine persulfide, which decomposes nonenzymatically into cysteine

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Although findings are often inconsistent and sometimes contradicted by other studies, certain clinical trials have reported improvements in semen parameters following antioxidant treatment, fueling heightened enthusiasm [38]

doi: 10.1016/j.xcrm.2022.100633 7