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Collagen, tissue, skin

A nonionic surfactant that deserves special attention is Cremophor EL (CrEL), which has been used for solubilization of a wide variety of hydrophobic drugs such as anaesthetics, photosensitizers, sedatives, immunosuppressive agents and anticancer drugs

Alogliptin (15 mg/kg/d for 24 weeks) decreased the atherosclerotic lesions and declined the elevated expressions of inflammatory markers IL-1 and IL-6 in ApoE-/- diabetic mice