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Portevin D, Auria CDS, Montrozier H, Houssin C, Stella A, Laneelle MA, et al

Validation of reference gene stability for APAP hepatotoxicity studies in different in vitro systems and identification of novel potential toxicity biomarkers

NAC is FDA approved with known pharmacokinetics and pharmacodynamics in human neonates and could rapidly be translated into a Phase 1 clinical trial for the treatment of NAS