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COVID-19 Presenting as Acute Bilateral Submassive Pulmonary Embolism in a Young Healthy Female

The changes include loss of collagen, elastin, fibroblast function, vascularity, and increased matrix metalloproteinase(s) enzymatic activities, resulting in cellular and extracellular degradation that leads to dryness, wrinkles, atrophy, impaired wound healing/barrier function, decreased antioxidant capacity [i.e., defense against reactive oxygen species (ROS) and oxidative stress], decreased attractiveness and psychological health, and increased perception of aging

Importantly, doses below 500 IU every other day showed inferior results