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NAC is also important for phase 2 liver detoxification, which is a crucial step in neutralizing potential toxins created during phase 1 detoxification

At the same time, increased visceral fat accumulation promotes lipolysis, resulting in elevated levels of free fatty acids that preferentially undergo -oxidation [84]

Mitochondria, endoplasmic reticulum (ER) and lysosomes can independently sense ROS levels and regulate local ROS microenvironment stability [140]

Future directions should therefore include strengthening air-quality policies, promoting clean cooking fuels, implementing national asthma education campaigns, integrating yoga and pulmonary rehabilitation into public sector respiratory services, expanding tobacco cessation services, and enhancing training of primary care physicians in guideline-based asthma management