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All analytical measurements were performed by Liquid Chromatography-Mass Spectrometry (LCMS) using a Shimadazu Nexera UPLC coupled to a SCIEX QTRAP 6500 Triple Quad mass spectrometer

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doi:10.1016/s1808-8694(15)30967-8

More recent work has shown that MOTS-C translocates to the nucleus under metabolic stress, where it regulates adaptive nuclear gene expression and influences whole-body energy metabolism (Kim et al., 2018