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Among the crosstalk between epithelial cells, smooth muscle cells, fibroblasts, neutrophils, and eosinophils, the architecture identified the following three crosstalk signaling pathways: EGFR signaling, TGF-1 signaling, and VEGF signaling

Protocadherin Beta 14 (PCDHB14), a member of the cadherin superfamily, is inactivated by aberrant methylation of its promoter in HCC patients and that PCDHB14 ablation inhibit cell cycle arrest, cell proliferation and ferroptosis (Liu Y