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Bottom Line: It is not that people are intolerant of histamine

Liao M, He X, Zhou Y, Peng W, Zhao X-M, Jiang M (2024) Coenzyme Q10 in atherosclerosis

Cytosolic mtDNA has been implicated in activating the cGAS-STING inflammation pathway, which contributes to inflammation in various diseases, including aging, systemic lupus erythematosus, and neurodegenerative conditions [29, 49, 50]