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Kisspeptin Kisspeptin is at the top of the reproductive hormone cascade by stimulating gonadotropin-releasing hormone (GnRH) neurons, which triggers LH and FSH secretion

What it looks like : Puffy face, fingers, or ankles Slight increase in body weight (often 37 lbs early in cycle) Sometimes accompanied by joint tightness or stiffness How to manage : Monitor sodium and potassium intake Add potassium-rich foods or supplements if bloated Drink 34 liters of water per day Use Krill Oil to reduce inflammation Reduce carbs slightly if retention persists beyond week 3 Short-term fluid retention is a known effect of GH elevation and typically normalizes within weeks as extracellular fluid volume stabilizes. Jaffe et al., Endocrinology and Metabolism Clinics 3

Evidence for cysteinesulphinate-independent pathways

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