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Key copper-dependent enzymes include: Superoxide Dismutase (SOD1): Antioxidant defense Cytochrome c Oxidase: Mitochondrial respiration Lysyl Oxidase: Collagen cross-linking Ceruloplasmin: Iron metabolism Matrix Remodeling & Collagen Synthesis One of the most extensively studied properties of GHK-Cu is its ability to influence extracellular matrix dynamics