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Srinivasan et al., 2005

oxyphylla fructus extract (360 mg/kg), the LPS-induced Alzheimers disease model demonstrated varying degrees of improvement as determined by the Y-maze test, the Morris water maze test, and histopathological investigation

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Loss-of-function missense mutations as well as single nucleotide polymorphisms in the genes encoding K ir 4.1 and AQP4 (which is selectively astroglial and operates in concert with K ir 4.1) are linked to epilepsy in humans