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In some cases..of cancer like in HCC, it has been found that endoplasmic reticulum stress-mediated activation of autophagy also plays a role in upregulating MRP1 that enhances intracellular drug or toxic heavy metal efflux thus protecting cells from apoptosis [362, 363]

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Using the FDA's body-surface-area conversion, a 10 mcg/kg rat dose maps to roughly 1.6 mcg/kg in a human, but most practitioners use higher doses based on clinical experience

Analyst 129(8):755758 Tang H, Chen J, Nie L, Yao S, Kuang Y (2006) Electrochemical oxidation of glutathione at well aligned carbon nanotube array electrode