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It can exist in different redox states (FADH2, FADH).[ref] Within the mitochondria, FAD and FMN also act as antioxidants, integral to activating the various enzymes that protect cells from oxidative stress, thus making adequate riboflavin essential for healthy mitochondria

Chem Res Toxicol 25:337347

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These mutations are located deep in the inter-subunit cleft, where small molecular volume changes are able to disrupt the dimer interface leading to more facile dissociation 20 (Fig