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Omori Y, Ohtani T, Sakata Y, Mano T, Takeda Y, Tamaki S, et al

Intestinal Hypoxia-Inducible Factor 2 Regulates Lactate Levels to Shape the Gut Microbiome and Alter Thermogenesis

Abbreviations: ALT alanine transaminase CYP the cytochrome P450 INR international normalized ratio References [1] Kur P, Kolasa-Woosiuk A, Misiakiewicz-Has K, Wiszniewska B

72 Chronic metformin treatment first became known as a pharmacological cause of vitamin B 12 deficiency within a decade of it coming into use and more recently decreased serum folate concentration has also been associated with its administration