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6) demonstrated that the gdh3 / gdh3 mutant exhibited a lower percentage of 13 C labelling of one to two carbon atoms in metabolites while a higher percentage of 13 C labelling for three or more carbon atoms in metabolites for most of TCA cycle intermediates and amino acids when compared to the wildtype

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In addition, according to the extension of epigenetics research, the United States NATIONAL Institutes of Health (NIH) in 2013 believed that epigenetics included both cells or individuals gene activity and expression inherited changes, and stable, long-term, and uninherited changes at the potential level of cell transcription