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However, the in vivo metabolic behavior and biocompatibility of GSH-CDs still require further and longer-term research and verification

Together, impaired viral clearance, low levels of type I interferons in the initial stage of infection, increased neutrophil extracellular traps and triggered NK cell activation constitute the plausible predisposing factors that drive the cytokine storm or cytokine storm syndrome in COVID-19 contributing to the aggressive inflammatory response

This work is motivated by several adverse effects that may occur in patients who have been exposed to denatured or non-native biological structures

doi: 10.1038/s41514-020-0042-x 81 Van LaethemAClaerhoutSGarmynMAgostinisP