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Front Genet 13:898204

The increases in TGF1 protein expression and SMAD3 phosphorylation induced by high glucose were significantly blocked in PSCs treated with GSH (Figs

These transcription factors are involved in the synthesis of several antioxidant enzymes (e.g., glutathione reductase, glutathione peroxidases, glutaredoxin, and glutathione- S -transferase), many of which are closely related to the cellular antioxidant, glutathione (Espinosa-Diez et al