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Another possibility is the use of dupilumab (IL-4/IL-13 receptor blocker), which has shown promising results in the treatment of various eosinophil-associated diseases including atopic dermatitis, asthma, nasal polyps, and eosinophilic esophagitis (232, 233)

Due to the presence of iron, hemoglobin imparts a red color to blood

Overexpression of insulin receptor substrate 1 (IRS1) relates to poor prognosis and promotes proliferation, stemness, migration, and oxidative stress resistance in cholangiocarcinoma

We further advocate for future studies in mammals to investigate the pharmacological restriction of exogenous thiols as a potentially safe and potent action to promote healthy ROS signaling and counteract aging