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Efficacy and Safety of Topical Tranexamic Acid Alone or in Combination with Either Fractional Carbon Dioxide Laser or Microneedling for the Treatment of Melasma

The activation of AMPK is linked to caloric restriction states where consumption of energy is reduced due to nutrition deprivation (Frank W Sellke, 2+ /calmodulin-dependent protein kinase kinase- (CaMKK)-dependent pathway (Shafique et al., 2013)

Isr Med Assoc J IMAJ 18(9):519524 Quintero OL, Amador-Patarroyo MJ, Montoya-Ortiz G, Rojas-Villarraga A, Anaya JM (2012) Autoimmune disease and gender: plausible mechanisms for the female predominance of autoimmunity