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Long-term anti-aging: The combination supports skin elasticity, collagen production, cellular repair, and overall vitality at the systemic level

however, no dose adjustments are needed based on renal function

To mitigate IGF-1 side effects such as joint pain, swelling, and nerve compression, bodybuilders can follow several strategies: use the lowest effective dose under medical supervision, rotate injection sites, maintain proper hydration, support joints with supplements like glucosamine or omega-3 fatty acids, and incorporate stretching and mobility exercises

These advanced biomimetic systems combine two or more cell types, including those derived from patients (Liu et al., 2025