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In this context, the anti-inflammatory properties of PYC, particularly its inhibition of the TLR4NF-B signaling pathway, represent a critical link between redox regulation and immune modulation ( Recent translational preclinical studies have explored the use of PYC-based nanocomposites as a strategy to enhance the delivery of antiviral agents, including molnupiravir, for the treatment of COVID-19 ( Overall, PYCs antiviral effects are likely mediated by a combination of direct viral inhibition and host-directed mechanisms, including modulation of oxidative stress and immune responses

The release rate of doxorubicin can be increased by using nanocarriers prepared by crosslinking bromelain with an ortho-ester-based crosslink agent

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Weighed cellular pellets were solubilized in ice-cold RIPA buffer (150 mM NaCl, 1% Nonidet NP-40, 1% sodium deoxycholate, 0.1% SDS, 50 mM Tris, pH 8.0) supplemented with a phosphatase inhibitor cocktail (1:200, Sigma-Aldrich P5726) and Benzonase nuclease (1:1000, Merck 70,664)