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A sample size calculation using a two-tailed t-test to achieve a power of 80% and alpha of 5%, with a SD = 0.8 and expected difference of 1.2 between groups, indicates that 9 women per study group would be required for the present study

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[1] Prior RSV infection or hospitalization does not preclude future vaccination, as natural immunity may not provide adequate long-term protection against subsequent severe disease