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Most of the supporting science involves the ingredients individually, often in oral supplement form rather than injectable, and frequently in specific patient populations like women with PCOS

The STEP 1 trial studied semaglutide 2.4 mg weekly in adults without diabetes and found 14.9% mean body weight loss versus 2.4% with placebo at 68 weeks

These repeated audits did not allow for GPs to treat patients as individuals

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