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STI + CoQ10 Group: The sciatic nerves of the rats in this group were treated with CoQ10 at a fixed dose of 10 mg/kg of rat body weight administered by gavage for 21 days consecutively after exposure to crush injury for 15 s

However, further prospective cohort studies with clinical endpoints in healthy subjects, and results from on-going randomized, placebo-controlled interventional trials are awaited to truly define the efficiency of homocysteine-lowering therapy in the prevention and correction of vascular disorders among patients with occlusive coronary artery, cerebrovascular and peripheral vascular diseases, and thrombosis related to hyperhomocysteinemia

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