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Description

LEAP2: liver-expressed antimicrobial peptide 2

In AD, dysregulated miRNAs such as miR-146a, miR-155, miR125b and miR-223-3p modulate key neuroinflammatory pathways

AGEs may cause vascular dysfunction by making cross-bonds between extracellular matrix proteins (elastin and collagen), which leads to blood vessel stiffness, heart fibrosis, and diastolic dysfunction 12

Both the gH/gL and gH/gL/gp42 repRNAs elicited neutralizing titers against EBV infection of epithelial and B cells that were boosted by a second immunization (Fig