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Drug Interactions CNS DepressantsWhen barbiturates, narcotics or other hypnotics (or systemic anesthetics), or other CNS depressants are to be given in conjunction with magnesium, their dosage should be adjusted with caution because of additive CNS depressant effects of magnesium

10.3343/alm.2015.35.1.1 59 KimK

The duration and severity of pretreatment deficiency symptoms have a clear impact on the time course and degree of recovery after starting B12 therapy [1,86], thus emphasizing the importance of early identification and prevention