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While certain tumor cells, like MDA-MB-231 cells, display positive durotaxis by moving from soft (0.5 kPa), to stiff (22 kPa) substrates [95, 96], others, such as U-251MG glioblastoma brain tumor cells, undergo negative durotaxis, migrating from 22 kPa regions towards softer, 10 kPa, areas [96]

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