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It is a reason to approach them the way you would any serious medicine, with evidence, supervision, and a clinician willing to tell you when the answer is no

Diarrhea Heart failure Dizziness Rash Nausea Flushing Increased blood sugar level Blurred vision Elevations in liver function tests Allergic sensitization Gastrointestinal distresses Liver toxicity Headache Pulmonary edema Congestive heart failure Polycythemia vera Itching Feeling of swelling of entire body Dysfunction of nerves resulting in numbness Pain Difficulty breathing Swelling of face Discoloration of urine Swelling of lips & tongue Restlessness Rapid swelling Ulcers Pruritus Escape of blood from a ruptured blood vessel Skin rash Cyanosis Skin irritation Contact allergies Optineuron Injection may also cause side-effects not listed here

Vitamin B12 (cobalamin) plays a key role in: Making healthy red blood cells (helping prevent certain types of anaemia) Supporting nerve function Helping normal energy metabolism Supporting cognitive function and mood (when deficiency is present) Because the body doesnt produce B12, we rely on dietary sources (primarily animal products and fortified foods) and on absorption through the gut