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A study (8) assessing the effects of oral administration of melatonin (3mg/day) in patients from day 5 until oocyte collection showed significant increase in fertilization rates as compared to the precedent cycle for the same patients (50% vs 20.2%)

(2017) 312:G145g52

Future research could further explore the role of potential pathways such as NF-B or MAPK, and evaluate the potential toxic side effects of pedunculagin on the liver and kidneys