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Key Takeaways CJC-1295 + Ipamorelin activates two distinct somatotroph receptors (GHRH-R and GHS-R1a) without overlapping desensitisation, producing synergistic GH release in published rodent and primate models The DAC moiety extends CJC-1295 half-life to 68 days

The genomics data for endogenous full-length ASXL1, BRD4 and BAP1, and for GFP-ASXL1 1-645 -WT, GFP-ASXL1 1-645 -I574D, BRD4 in GFP-ASXL1 1-645 -WT and BRD4 in GFP-ASXL1 1-645 -I574D generated in this study have been deposited in the Gene Expression Omnibus database under accession code GSE302969

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