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Current evidence-based guidelines emphasize the value of multimodal treatments, which encompass both non-pharmacological and selected pharmacological treatments tailored to individual symptoms, including pain, fatigue, sleep problems and mood problems

doi: 10.3389/fphar.2021.773909 65 YangBCLeungPS

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation