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Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: Has the time come

Pairing copper peptides with other actives (the works well part, with common-sense rules) Copper peptides are often described as playing well with other actives, but the real trick is not throwing everything on your face at once

hPSCs were dissociated into single-cell suspensions using TrypLE Select (Thermo Fisher Scientific, Netherlands) and plated at a density of 2 10 6 cells/well in Stem Flex medium (Thermo Fisher Scientific, Netherlands) supplemented with 10 M Y-27632 (Peprotech, USA) on Geltrex-coated 6-well plates (Eppendorf, Germany) under a 5% CO 2 atmosphere

GFW: reports funding or honoraria from Amgen, Pfizer, Esperion, Arrowhead, Regeneron, Sanofi, AstraZeneca, Novartis