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Understanding the Bodys Master Antioxidant Glutathione is a small but mighty molecule produced naturally within almost every cell of the human body

monocytogenes synthesizes ActA and InlK proteins that attract host actin and major vault protein and thus camouflages under the host proteins and thereby inhibits detection by autophagy receptors ( Francisella tularensis synthesizes O-antigen polysaccharides that protect the bacterium from cytosolic sensors, thus evading autophagic targeting (Jessop et al., 2025)

Conclusion Our study highlights the potential of targeting antioxidant defense mechanisms to sensitize cancer cells to chemotherapy

The 5-FU mouse model was selected because it is rapidly developed, cost-effective, and closely reflects the pathological features observed in human CIM, making it a widely used approach for evaluating therapeutic candidates (Huang et al