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On the other hand, acetylation and methylation are altered in Rett syndrome, an autism spectrum disorder caused by mutations in MeCP2, a global transcriptional repressor of methylated promoters during postnatal brain development [137]

A comprehensive meta-analysis of ASD animal models revealed significantly elevated p-AKT protein expression in cortical tissues [30]

539,540 Lifestyle interventions, such as a healthy diet, regular physical activity, and smoking cessation, are essential in managing PDPN by improving glycemic control, enhancing nerve function, and reducing pain perception