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A final alternative to alleviate FcRn-controlled pathological mechanisms could be to alter FcRn in itself, as may be intended with a gene therapy being developed in a collaboration between Beam and Apellis for a one-time dose of gene-editing molecules targeting FcRn [436, 437]

Even when Im having a viewing session with producers, [a nurse] just sticks the needle in me and we carry on whatever we are doing, he told the US edition of GQ in 2011

Injections quickly correct severe cases and absorption problems, while oral regimens suit many with mild or moderate deficiency, offering convenience and cost savings

The risk of reduced potency or contamination is not worth the savings from squeezing out a few extra doses