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Bot M, Brouwer IA, Roca M, Kohls E, Penninx B, Watkins E, et al

A robust detoxification system is necessary to reduce the oxidative stress of this toxic burden

These changes highlight the importance of evolving operational strategies to remain competitive

Within cellular microenvironments, this process is frequently coupled with the Haber-Weiss reaction, wherein the superoxide anion (O 2 - ) from mitochondria continuously reduces Fe 3+ back to Fe 2+ , creating a self-sustaining and vicious cycle of radical generation [51,52]