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Soc Sci Med 222:335345

This changed recently in high-income countries, where cancer is now responsible for twice as many deaths as cardiovascular diseases (Dagenais et al., 2019)

In EC, NADPH can be generated by three pathways: glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (PGD) in oxidative pentose phosphate pathway (oxPPP), malic enzymes (MEs) in glutaminolysis, and methylenetetrahydrofolate dehydrogenase (MTHFD) in folate metabolism

Another study found that patients hospitalized for acute mania were 5.5 times more likely to have used systemic antibiotics in the preceding 3 days than controls (Yolken et al., 2016)