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These properties make it particularly relevant in contexts where oxidative stress drives tissue damage: photoaging, COPD, post-injury inflammation, and metabolic disease

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Another study developed phasetransitional Pt (IV) NPcRGD nanoparticles with a hybrid lipidpolymer shell for ovarian cancer, which are both GSHsensitive and ultrasoundresponsive, demonstrating enhanced therapeutic efficacy and reduced side effects in in vivo models [121]

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