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doi:10.1021/bi400191z

PD: Parkinsons disease

ER and ER are nuclear receptors that, upon ligand binding, modulate gene expression through direct interaction with estrogen response elements (EREs) or via cross-talk with transcription factors such as FOXO and CREB (Wang et al., 2012)

Reduction in the activity of this enzyme decreases the conversion of substrates into fatty acids, thereby shifting cellular metabolism toward lipid mobilization rather than storage [1]