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Even those who get enough in their diet can be deficient in the vitamin if they have certain medical conditions or take specific medications

Definition Box Signal Peptide: A short peptide sequence that triggers downstream cellular responses (gene expression, enzyme activation, cytokine release) by interacting with receptors or transport proteins rather than by being incorporated into larger structures

14E/17R mutations expected to stabilize the central helix via a salt bridge, 25P/ 28P/29P mutations as in rat amylin to reduce -sheet propensity and fibril formation

However, since no direct studies support the use of B12 injections for weight loss, more research is warranted