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Proinflammatory cytokine-induced alpha cell impairment in human islet microtissues is partially restored by dual incretin receptor agonism

(Scientific Reports, 2021) reported that NNMT inhibition plus a lean-diet substitution lowered body weight, fat mass, and liver fat beyond either intervention alone

Some sources suggest the compound is well-absorbed orally based on rat pharmacokinetic data, while others argue that subcutaneous injection provides more reliable absorption