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Synergistic reversal of inflammation-mediated degeneration in intervertebral discs: phenylboric acid-grafted hyaluronic acid hydrogel as an anti-oxidative vehicle for Timp-3 delivery and promotion of extracellular matrix synthesis

The authors proposed the following model of Se uptake to the brain via SELENOP-LRP8: SELENOP present in blood and CSF is taken up by LRP8-positive cells of BBB and BCB, resynthesized in neighboring astrocytes, and subsequently released to supply LRP8-positive neurons within the brain with Se Figure 2

The abdomen typically has consistent subcutaneous fat depth and good absorption

Contamination possible if poor handling or temperature abuse