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In some cases, lower doses can also cause toxicity over time

Uptake studies confirmed Seo1p as a high affinity (Km =48uM), highly specific transporter of -Glu-met since other analogs like n-Glu-met, -Glu-leu, -Glu-cys, -Glu-met-gly, methionine and methionine sulfoxide were not transported by Seo1p

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