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The manufacturer provided that the Game Ready System has FDA clearance and is indicated for to treat post-surgical and acute injuries to reduce edema, swelling, and pain where cold and compression are indicated

L., Hunter, K

Decreased membrane polarization can be an indicator that the mitochondria are uncoupled, meaning that protons are translocating across the inner mitochondrial membrane through a mechanism other than ATP synthase, and are thus not used to make ATP