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constructed a single-cell transcriptomic atlas of maize roots under heat stress, discovering that the cortex is the principal root cell type responding to heat stress with the highest number of differentially expressed genes, whose developmental trajectory is preferentially affected under heat stress (Wang et al., 2025)

These therapeutic effects appear to be mediated through curcumins modulation of key neuromodulators, with particularly noteworthy differential regulation observed between brain and gut tissues: while BDNF and phosphorylated CREB (p-CREB) levels increased in hippocampal tissue, their expression decreased in colonic tissues (Yu et al., 2015)

10.1021/jf8007212 144 LuoC.SongW.ChenQ.ZhengZ.ChenK.CaoB.et al (2014)

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