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These autoantibodies against immunomodulatory proteins (including cytokines, chemokines, complement components and cell-surface proteins) could attack tissues of patients, thereby impair host cell signals, perturb immune function, damage organ systems, and increase COVID-19 severity 36

Thyroid 24 , 16701751 (2014)

The most effective ways to manage them are maintaining a regular eating schedule (blood sugar dips are a major craving trigger), staying well hydrated, exercising daily to restore dopamine balance, keeping a craving diary to identify patterns and triggers, and having a prepared plan for high-risk moments such as social events or stressful evenings