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The expression of nutrient transporters, such as GLUT1 and LAT1, has been shown to be high in both, the BBB and in glioma (207, 208), which led to the development of different transporter-utilizing anti-cancer drug delivery strategies in order to reach the cancer cells residing beyond the intact BBB (Table II)

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revealed punctate hyperintensities in some patients, suggesting cerebral microvascular damage and fibrinogen leakage [329]

However, if they cant quit well in advance of surgery, she advises that they at least refrain from smoking for several hours beforehand