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These effects are usually temporary and mild

The action of withanolides, steroidal lactone triterpenoids, which share chemical structural similarities with testosterone and may therefore mimic the effects of male steroidal hormones, is another way that ashwagandha affects the reproductive system and fecundity [203]

Eisalou MY, Farahpour MR

Early trials have confirmed pharmacodynamic markers such as interferon induction, T cell activation and local remodeling of cytokine profiles, but durable survival benefits remain to be established [76, 81, 83]