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Human Trx and GSH systems have compensatory activities so that inhibition of one arm can be supplemented by the other 60 , suggesting that the inhibition of hTrxR by some of the compounds presented here will not be detrimental for humans as it is for schistosomes

Estradiol protects clomiphene citrate-induced apoptosis in ovarian follicular cells and ovulated cumulus-oocyte complexes

In a randomized trial, SCFA-enriched fiber reduced both plasma pCG and blood pressure, consistent with a microbiota-mediated shift toward reduced tyrosine fermentation (Xu et al