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They reported that the effect of DPP4 inhibitors on the body weight of women with PCOS is based on the increase in the growth hormone levels, which are lowered in PCOS patients

In addition, estradiol enhances IgG and IgM production by PBMC, which leads to elevated levels of polyclonal IgG, including IgG anti-DNA in PBMC of SLE patients by enhancing B cell activity via interleukin 10 [33]